Photo report

IPBS - Pharmacology and Structural Biology Institute

IPBS - Pharmacology and Structural Biology Institute

20160102_0010
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20160102_0010
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Observation of mouse lung sections infected by the pulmonary pathogen Mycobacterium tuberculosis (Mtb), the pathogen of tuberculosis. Researchers quantified the degree of inflammation in these sections. They compared infection by the wild strain of Mtb with a mutated Mtb strain, looking for a gene implicated in the virulence of the inflammation. They were able to confirm that the mutant generates a lower degree of inflammation than the wild strain, evidence that the mutant may be less virulent…

Photo
20160102_0010
Observation of mouse lung sections infected by the pathogen of tuberculosis
20160102_0047
Open media modal

A mixture of antibodies was deposited on pre-treated glass slides on which sections of subcutaneously induced murine fibrosarcoma had been placed. The fibrosarcoma models spontaneously generated HEV blood vessels (high endothelium veinules) 8 days after induction in the mouse. Researchers were seeking to detect the presence of specific RNA for these blood vessels on the glass slides. The antibodies will be used to co-mark the RNA of these vessels.

Photo
20160102_0047
A mixture of antibodies was deposited on pre-treated glass slides
20160102_0051
Open media modal

Observation by confocal microscope of glass slides on which sections of murine fibrosarcoma induced subcutaneously in mice were placed. The fibrosarcoma models spontaneously generated HEV blood vessels (high endothelium veinules) 8 days after induction in the mouse. Researchers were seeking to detect the presence of specific RNA for these blood vessels on the glass slides. They thus marked the RNA of these vessels with antibodies.

Photo
20160102_0051
Glass slides on which sections of murine fibrosarcoma were placed
20160102_0050
Open media modal

Observation by confocal microscope of glass slides on which sections of murine fibrosarcoma induced subcutaneously in mice were placed. The fibrosarcoma models spontaneously generated HEV blood vessels (high endothelium veinules) 8 days after induction in the mouse. Researchers were seeking to detect the presence of specific RNA for these blood vessels on the glass slides. They thus marked the RNA of these vessels with antibodies.

Photo
20160102_0050
Glass slides on which sections of murine fibrosarcoma were placed
20160102_0049
Open media modal

A mixture of antibodies was deposited on pre-treated glass slides on which sections of subcutaneously induced murine fibrosarcoma had been placed. The fibrosarcoma models spontaneously generated HEV blood vessels (high endothelium veinules) 8 days after induction in the mouse. Researchers were seeking to detect the presence of specific RNA for these blood vessels on the glass slides. The antibodies will be used to co-mark the RNA of these vessels.

Photo
20160102_0049
A mixture of antibodies was deposited on pre-treated glass slides
20160102_0048
Open media modal

A mixture of antibodies was deposited on pre-treated glass slides on which sections of subcutaneously induced murine fibrosarcoma had been placed. The fibrosarcoma models spontaneously generated HEV blood vessels (high endothelium veinules) 8 days after induction in the mouse. Researchers were seeking to detect the presence of specific RNA for these blood vessels on the glass slides. The antibodies will be used to co-mark the RNA of these vessels.

Photo
20160102_0048
A mixture of antibodies was deposited on pre-treated glass slides
20160102_0046
Open media modal

Sections of murine fibrosarcoma induced subcutaneously in mice placed on glass slides were circled using an ImmunoMarker. The fibrosarcoma models spontaneously generated HEV blood vessels (high endothelium veinules) 8 days after induction in the mouse. Researchers were seeking to detect the presence of specific RNA for these blood vessels on the glass slides. They therefore deposited a mixture of antibodies on the sections in order to co-mark the RNA of the vessels. The ImmunoMarker formed a…

Photo
20160102_0046
Sections of murine fibrosarcoma placed on glass slides were circled using an ImmunoMarker
20160102_0045
Open media modal

Sections of murine fibrosarcoma induced subcutaneously in mice placed on glass slides were circled using an ImmunoMarker. The fibrosarcoma models spontaneously generated HEV blood vessels (high endothelium veinules) 8 days after induction in the mouse. Researchers were seeking to detect the presence of specific RNA for these blood vessels on the glass slides. They therefore deposited a mixture of antibodies on the sections in order to co-mark the RNA of the vessels. The ImmunoMarker formed a…

Photo
20160102_0045
Sections of murine fibrosarcoma placed on glass slides were circled using an ImmunoMarker
20160102_0044
Open media modal

Preparation of a mixture of antibodies to be deposited on pre-treated glass slides, on which sections of subcutaneously induced murine fibrosarcoma had been placed. The fibrosarcoma models spontaneously generated HEV blood vessels (high endothelium veinules) 8 days after induction in the mouse. Researchers were seeking to detect the presence of specific RNA for these blood vessels on the glass slides. The antibodies will be used to co-mark the RNA of these vessels.

Photo
20160102_0044
Preparation of a mixture of antibodies to be deposited on pre-treated glass slides
20160102_0043
Open media modal

Withdrawal of subcutaneously induced murine fibrosarcoma sections dipped for smoothing in a 37°C bath. These sections were paraffin-embedded. They were then deposited on glass slides. The fibrosarcoma models spontaneously generated HEV blood vessels (high endothelium veinules) 8 days after induction in the mouse. Researchers were seeking to detect the presence of specific RNA for these blood vessels on the glass slides. They thus co-marked this RNA using specific proteins for these vessels.

Photo
20160102_0043
Withdrawal of subcutaneously induced murine fibrosarcoma sections dipped in a 37°C bath
20160102_0042
Open media modal

Withdrawal of subcutaneously induced murine fibrosarcoma sections dipped for smoothing in a 37°C bath. These sections were paraffin-embedded. They were then deposited on glass slides. The fibrosarcoma models spontaneously generated HEV blood vessels (high endothelium veinules) 8 days after induction in the mouse. Researchers were seeking to detect the presence of specific RNA for these blood vessels on the glass slides. They thus co-marked this RNA using specific proteins for these vessels.

Photo
20160102_0042
Withdrawal of subcutaneously induced murine fibrosarcoma sections dipped in a 37°C bath
20160102_0041
Open media modal

Withdrawal of subcutaneously induced murine fibrosarcoma sections dipped for smoothing in a 37°C bath. These sections were paraffin-embedded. They were then deposited on glass slides. The fibrosarcoma models spontaneously generated HEV blood vessels (high endothelium veinules) 8 days after induction in the mouse. Researchers were seeking to detect the presence of specific RNA for these blood vessels on the glass slides. They thus co-marked this RNA using specific proteins for these vessels.

Photo
20160102_0041
Withdrawal of subcutaneously induced murine fibrosarcoma sections dipped in a 37°C bath
20160102_0040
Open media modal

Microtome section of murine fibrosarcomas induced subcutaneously in mice. These paraffin-embedded tumour tissues were placed on glass slides. The fibrosarcoma models spontaneously generated HEV blood vessels (high endothelium veinules) 8 days after induction in the mouse. Researchers were seeking to detect the presence of specific RNA for these blood vessels on the glass slides. They thus co-marked this RNA using specific proteins for these vessels.

Photo
20160102_0040
Microtome section of murine fibrosarcomas induced subcutaneously in mice
20160102_0039
Open media modal

Microtome section of murine fibrosarcomas induced subcutaneously in mice. These paraffin-embedded tumour tissues were placed on glass slides. The fibrosarcoma models spontaneously generated HEV blood vessels (high endothelium veinules) 8 days after induction in the mouse. Researchers were seeking to detect the presence of specific RNA for these blood vessels on the glass slides. They thus co-marked this RNA using specific proteins for these vessels.

Photo
20160102_0039
Microtome section of murine fibrosarcomas induced subcutaneously in mice
20160102_0066
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Injecting the surface of a small slice of human dermal tissue with a GFP-expressing plasmid (Green Fluorescent Protein, a protein that emits fluorescent green light). This tissue is a dermal substitute engineered from cells taken during a skin biopsy. The tissue was positioned between electrodes connected to a generator which transmitted electrical impulses with known parameters. These pulses induced a transitory permeabilisation of the membranes of the tissue cells and enabled the GFP…

Photo
20160102_0066
Slice of human dermal tissue is positioned between electrodes connected to a generator
20160102_0074
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Analysis of fluorescence images of the extracellular matrix of a bacterial biofilm of S. epidermidis, positioned under a fluorescence microscope (in the background). Copper electrodes were connected to a generator by means of two alligator clips. The biofilms were then subjected to pulsed electric fields in order to disorganise the bacteria. The aim was to understand how the extracellular matrix is organised and how the pulsed electric fields can disorganise it. The long term goal is to use…

Photo
20160102_0074
Fluorescence images of the extracellular matrix of a bacterial biofilm of S. epidermidis
20160102_0073
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Fluorescence excitation of bacterial biofilms of S. epidermidis, positioned under a fluorescence microscope. Copper electrodes were connected to a generator by means of two alligator clips. The biofilms were then subjected to pulsed electric fields in order to disorganise the bacteria. The extracellular matrix of the biofilms can be seen directly by microscopy. The purpose was to find a new non-invasive method to combat the pathogenic bacteria involved in nosocomial diseases.

Photo
20160102_0073
Fluorescence excitation of bacterial biofilms of S. epidermidis
20160102_0072
Open media modal

Bacterial biofilms of S. epidermidis positioned under a fluorescence microscope. Copper electrodes were connected to a generator by means of two alligator clips. The biofilms were then subjected to pulsed electric fields in order to disorganise the bacteria. A Labtech glass slide system was used to visualise the biofilms under the microscope. The purpose was to find a new non-invasive method to combat the pathogenic bacteria involved in nosocomial diseases.

Photo
20160102_0072
Bacterial biofilms of S. epidermidis positioned under a fluorescence microscope
20160102_0071
Open media modal

Bacterial biofilms of S. epidermidis positioned under a fluorescence microscope. Copper electrodes were connected to a generator by means of two alligator clips. The biofilms were then subjected to pulsed electric fields in order to disorganise the bacteria. A Labtech glass slide system was used to visualise the biofilms under the microscope. The purpose was to find a new non-invasive method to combat the pathogenic bacteria involved in nosocomial diseases.

Photo
20160102_0071
Bacterial biofilms of S. epidermidis positioned under a fluorescence microscope
20160102_0069
Open media modal

Apparatus in which a small slice of human dermal tissue was placed between electrodes connected to a generator. This tissue was a dermal substitute engineered from cells taken during a skin biopsy. The generator transmitted electrical impulses with known parameters to induce a transitory permeabilisation of the membranes of the tissue cells and enable a GFP-expressing plasmid (Green Fluorescent Protein a protein that emits fluorescent green light) to penetrate the cells. After 24 or 48 hours,…

Photo
20160102_0069
Slice of human dermal tissue is positioned between electrodes connected to a generator
20160102_0068
Open media modal

Apparatus in which a small slice of human dermal tissue was placed between electrodes connected to a generator. This tissue was a dermal substitute engineered from cells taken during a skin biopsy. The generator transmitted electrical impulses with known parameters to induce a transitory permeabilisation of the membranes of the tissue cells and enable a GFP-expressing plasmid (Green Fluorescent Protein a protein that emits fluorescent green light) to penetrate the cells. After 24 or 48 hours,…

Photo
20160102_0068
Slice of human dermal tissue is positioned between electrodes connected to a generator
20160102_0067
Open media modal

Application of a pulsed electric field to a slice of human dermal tissue. This tissue is a dermal substitute engineered from cells taken during a skin biopsy. The tissue was placed between electrodes connected to a generator (in yellow). The generator transmitted electrical impulses with known parameters to induce a transitory permeabilisation of the cell membranes of the tissue and enable a GFP-expressing plasmid (Green Fluorescent Protein, a protein that emits fluorescent green light) to…

Photo
20160102_0067
Application of a pulsed electric field to a slice of human dermal tissue
20160102_0038
Open media modal

After the microtome sectioning of murine fibrosarcoma induced subcutaneously in mice, the paraffin-embedded tumour sections were transferred for smoothing to a 37°C bath. They were then deposited on glass slides. The fibrosarcoma models spontaneously generated HEV blood vessels (high endothelium veinules) 8 days after induction in the mouse. Researchers were seeking to detect the presence of specific RNA for these blood vessels on the glass slides. They thus co-marked this RNA using specific…

Photo
20160102_0038
Transfer of the paraffin-embedded tumour sections for smoothing to a 37°C bath
20160102_0065
Open media modal

Adjusting the apparatus in which a slice of human dermal tissue is positioned between electrodes connected to a generator. This tissue was a dermal substitute engineered from cells taken during a skin biopsy. The generator transmitted electrical impulses with known parameters to induce a transitory permeabilisation of the membranes of the tissue cells and enable a GFP-expressing plasmid (Green Fluorescent Protein a protein that emits fluorescent green light) to penetrate the cells. After 24 or…

Photo
20160102_0065
Slice of human dermal tissue is positioned between electrodes connected to a generator
20160102_0064
Open media modal

A small slice of human dermal tissue placed between electrodes connected to a generator. This tissue was a dermal substitute engineered from cells taken during a skin biopsy. The generator transmitted electrical impulses with known parameters to induce a transitory permeabilisation of the membranes of the tissue cells and enable a GFP-expressing plasmid (Green Fluorescent Protein a protein that emits fluorescent green light) to penetrate the cells. After 24 or 48 hours, the tissue was examined…

Photo
20160102_0064
A small slice of human dermal tissue placed between electrodes connected to a generator
20160102_0063
Open media modal

A small slice of human dermal tissue placed in a Petri dish. This tissue is a dermal substitute engineered from cells taken during a skin biopsy. A pulsed electric field was applied to this tissue to help a GFP-expressing plasmid (Green Fluorescent Protein, a protein that emits green fluorescent light) penetrate its cells. After 24 or 48 hours, the tissue was examined by multiphoton microscope in order to locate and quantify the amount of GFP-expressing cells. This experiment enabled us to…

Photo
20160102_0063
A small slice of human dermal tissue placed in a Petri dish
20160102_0062
Open media modal

This tissue slice is a dermal substitute engineered from cells taken during a skin biopsy. A pulsed electric field was applied to this tissue to help a GFP-expressing plasmid (Green Fluorescent Protein, a protein that emits green fluorescent light) penetrate its cells. After 24 or 48 hours, the tissue was examined by multiphoton microscope in order to locate and quantify the amount of GFP-expressing cells. This experiment enabled us to obtain in vitro rates of transfection comparable to those…

Photo
20160102_0062
This tissue slice is a dermal substitute engineered from cells taken during a skin biopsy
20160102_0061
Open media modal

This tissue slice is a dermal substitute engineered from cells taken during a skin biopsy. A pulsed electric field was applied to this tissue to help a GFP-expressing plasmid (Green Fluorescent Protein, a protein that emits green fluorescent light) penetrate its cells. After 24 or 48 hours, the tissue was examined by multiphoton microscope in order to locate and quantify the amount of GFP-expressing cells. This experiment enabled us to obtain in vitro rates of transfection comparable to those…

Photo
20160102_0061
This tissue slice is a dermal substitute engineered from cells taken during a skin biopsy
20160102_0060
Open media modal

Sampling a small slice of human dermal tissue from a 24-well plate. This tissue is a dermal substitute engineered from cells taken during a skin biopsy. A pulsed electric field was applied to this tissue to help a GFP-expressing plasmid (Green Fluorescent Protein, a protein that emits green fluorescent light) penetrate its cells. After 24 or 48 hours, the tissue was examined by multiphoton microscope in order to locate and quantify the amount of GFP-expressing cells. This experiment enabled us…

Photo
20160102_0060
Sampling a small slice of human dermal tissue from a 24-well plate
20160102_0059
Open media modal

Sampling a small slice of human dermal tissue from a 24-well plate. This tissue is a dermal substitute engineered from cells taken during a skin biopsy. A pulsed electric field was applied to this tissue to help a GFP-expressing plasmid (Green Fluorescent Protein, a protein that emits green fluorescent light) penetrate its cells. After 24 or 48 hours, the tissue was examined by multiphoton microscope in order to locate and quantify the amount of GFP-expressing cells. This experiment enabled us…

Photo
20160102_0059
Sampling a small slice of human dermal tissue from a 24-well plate
20160102_0011
Open media modal

Observation of mouse lung sections infected by the pulmonary pathogen Mycobacterium tuberculosis (Mtb), the pathogen of tuberculosis. Researchers quantified the degree of inflammation in these sections. They compared infection by the wild strain of Mtb with a mutated Mtb strain, looking for a gene implicated in the virulence of the inflammation. They were able to confirm that the mutant generates a lower degree of inflammation than the wild strain, evidence that the mutant may be less virulent…

Photo
20160102_0011
Observation of mouse lung sections infected by the pathogen of tuberculosis
20160102_0019
Open media modal

Observation of mouse lung sections infected by the pulmonary pathogen Mycobacterium tuberculosis (Mtb), the pathogen of tuberculosis. Researchers quantified the degree of inflammation in these sections. They compared infection by the wild strain of Mtb with a mutated Mtb strain, looking for a gene implicated in the virulence of the inflammation. They were able to confirm that the mutant generates a lower degree of inflammation than the wild strain, evidence that the mutant may be less virulent.

Photo
20160102_0019
Mouse lung sections infected by the pathogen of tuberculosis
20160102_0018
Open media modal

Sections of mouse colon coloured in alcian blue in order to detect the very abundant mucus at this level of the intestine. Researchers sought to optimize the preparation of the colon sections so as to preserve this mucus, the presence of which is easily checked by the colour. Their aim was to preserve the intestinal microbiota associated with the mucus. In the longer term, they are eager to observe this microbiota by microscopy using specific Fluorescence In Situ Hybridization (FISH) probes, in…

Photo
20160102_0018
Sections of mouse colon coloured in alcian blue in order to detect the very abundant mucus
20160102_0017
Open media modal

Sections of mouse colon coloured in alcian blue in order to detect the very abundant mucus at this level of the intestine. Researchers sought to optimize the preparation of the colon sections so as to preserve this mucus, the presence of which is easily checked by the colour. Their aim was to preserve the intestinal microbiota associated with the mucus. In the longer term, they are eager to observe this microbiota by microscopy using specific Fluorescence In Situ Hybridization (FISH) probes, in…

Photo
20160102_0017
Sections of mouse colon coloured in alcian blue in order to detect the very abundant mucus
20160102_0016
Open media modal

Sections of mouse colon coloured in alcian blue in order to detect the very abundant mucus at this level of the intestine. Researchers sought to optimize the preparation of the colon sections so as to preserve this mucus, the presence of which is easily checked by the colour. Their aim was to preserve the intestinal microbiota associated with the mucus. In the longer term, they are eager to observe this microbiota by microscopy using specific Fluorescence In Situ Hybridization (FISH) probes, in…

Photo
20160102_0016
Sections of mouse colon coloured in alcian blue in order to detect the very abundant mucus
20160102_0015
Open media modal

Observation of mouse lung sections infected by the pulmonary pathogen Mycobacterium tuberculosis (Mtb), the pathogen of tuberculosis. Researchers quantified the degree of inflammation in these sections. They compared infection by the wild strain of Mtb with a mutated Mtb strain, looking for a gene implicated in the virulence of the inflammation. They were able to confirm that the mutant generates a lower degree of inflammation than the wild strain, evidence that the mutant may be less virulent…

Photo
20160102_0015
Observation of mouse lung sections infected by the pathogen of tuberculosis
20160102_0014
Open media modal

Observation of mouse lung sections infected by the pulmonary pathogen Mycobacterium tuberculosis (Mtb), the pathogen of tuberculosis. Researchers quantified the degree of inflammation in these sections. They compared infection by the wild strain of Mtb with a mutated Mtb strain, looking for a gene implicated in the virulence of the inflammation. They were able to confirm that the mutant generates a lower degree of inflammation than the wild strain, evidence that the mutant may be less virulent…

Photo
20160102_0014
Observation of mouse lung sections infected by the pathogen of tuberculosis
20160102_0013
Open media modal

Observation of mouse lung sections infected by the pulmonary pathogen Mycobacterium tuberculosis (Mtb), the pathogen of tuberculosis. Researchers quantified the degree of inflammation in these sections. They compared infection by the wild strain of Mtb with a mutated Mtb strain, looking for a gene implicated in the virulence of the inflammation. They were able to confirm that the mutant generates a lower degree of inflammation than the wild strain, evidence that the mutant may be less virulent…

Photo
20160102_0013
Observation of mouse lung sections infected by the pathogen of tuberculosis
20160102_0012
Open media modal

Observation of mouse lung sections infected by the pulmonary pathogen Mycobacterium tuberculosis (Mtb), the pathogen of tuberculosis. Researchers quantified the degree of inflammation in these sections. They compared infection by the wild strain of Mtb with a mutated Mtb strain, looking for a gene implicated in the virulence of the inflammation. They were able to confirm that the mutant generates a lower degree of inflammation than the wild strain, evidence that the mutant may be less virulent…

Photo
20160102_0012
Observation of mouse lung sections infected by the pathogen of tuberculosis
20160102_0020
Open media modal

Observation of mouse lung sections infected by the pulmonary pathogen Mycobacterium tuberculosis (Mtb), the pathogen of tuberculosis. Researchers quantified the degree of inflammation in these sections. They compared infection by the wild strain of Mtb with a mutated Mtb strain, looking for a gene implicated in the virulence of the inflammation. They were able to confirm that the mutant generates a lower degree of inflammation than the wild strain, evidence that the mutant may be less virulent.

Photo
20160102_0020
Mouse lung sections infected by the pathogen of tuberculosis
20160102_0009
Open media modal

Observation of mouse lung sections infected by the pulmonary pathogen Mycobacterium tuberculosis (Mtb), the pathogen of tuberculosis. Researchers quantified the degree of inflammation in these sections. They compared infection by the wild strain of Mtb with a mutated Mtb strain, looking for a gene implicated in the virulence of the inflammation. They were able to confirm that the mutant generates a lower degree of inflammation than the wild strain, evidence that the mutant may be less virulent…

Photo
20160102_0009
Observation of mouse lung sections infected by the pathogen of tuberculosis
20160102_0029
Open media modal

Observation by fluorescence microscope of cells infected by HIV and stained for immunofluorescence. Human macrophages, immune cells, were extracted from the blood of healthy donors. These were then put into culture and co-infected with HIV and Mycobacterium tuberculosis, the agent responsible for tuberculosis. The infected cells were stained with visible fluorescent antibodies which specifically recognize HIV. These immunofluorescence experiments were designed to monitor the development of the…

Photo
20160102_0029
Cells infected by HIV and stained for immunofluorescence
20160102_0037
Open media modal

After the microtome sectioning of murine fibrosarcoma induced subcutaneously in mice, the paraffin-embedded tumour sections were transferred for smoothing to a 37°C bath. They were then deposited on glass slides. The fibrosarcoma models spontaneously generated HEV blood vessels (high endothelium veinules) 8 days after induction in the mouse. Researchers were seeking to detect the presence of specific RNA for these blood vessels on the glass slides. They thus co-marked this RNA using specific…

Photo
20160102_0037
Transfer of the paraffin-embedded tumour sections for smoothing to a 37°C bath
20160102_0036
Open media modal

Microtome section of murine fibrosarcomas induced subcutaneously in mice. These paraffin-embedded tumour tissues were placed on glass slides. The fibrosarcoma models spontaneously generated HEV blood vessels (high endothelium veinules) 8 days after induction in the mouse. Researchers were seeking to detect the presence of specific RNA for these blood vessels on the glass slides. They thus co-marked this RNA using specific proteins for these vessels.

Photo
20160102_0036
Microtome section of murine fibrosarcomas induced subcutaneously in mice
20160102_0035
Open media modal

Microtome section of murine fibrosarcomas induced subcutaneously in mice. These paraffin-embedded tumour tissues were placed on glass slides. The fibrosarcoma models spontaneously generated HEV blood vessels (high endothelium veinules) 8 days after induction in the mouse. Researchers were seeking to detect the presence of specific RNA for these blood vessels on the glass slides. They thus co-marked this RNA using specific proteins for these vessels.

Photo
20160102_0035
Microtome section of murine fibrosarcomas induced subcutaneously in mice
20160102_0034
Open media modal

After the microtome sectioning of murine fibrosarcoma induced subcutaneously in mice, the paraffin-embedded tumour sections were transferred for smoothing to a 37°C bath. They were then deposited on glass slides. The fibrosarcoma models spontaneously generated HEV blood vessels (high endothelium veinules) 8 days after induction in the mouse. Researchers were seeking to detect the presence of specific RNA for these blood vessels on the glass slides. They thus co-marked this RNA using specific…

Photo
20160102_0034
Transfer of the paraffin-embedded tumour sections for smoothing to a 37°C bath
20160102_0033
Open media modal

Microtome section of murine fibrosarcomas induced subcutaneously in mice. These paraffin-embedded tumour tissues were placed on glass slides. The fibrosarcoma models spontaneously generated HEV blood vessels (high endothelium veinules) 8 days after induction in the mouse. Researchers were seeking to detect the presence of specific RNA for these blood vessels on the glass slides. They thus co-marked this RNA using specific proteins for these vessels.

Photo
20160102_0033
Microtome section of murine fibrosarcomas induced subcutaneously in mice
20160102_0032
Open media modal

Microtome section of murine fibrosarcomas induced subcutaneously in mice. These paraffin-embedded tumour tissues were placed on glass slides. The fibrosarcoma models spontaneously generated HEV blood vessels (high endothelium veinules) 8 days after induction in the mouse. Researchers were seeking to detect the presence of specific RNA for these blood vessels on the glass slides. They thus co-marked this RNA using specific proteins for these vessels.

Photo
20160102_0032
Microtome section of murine fibrosarcomas induced subcutaneously in mice
20160102_0031
Open media modal

Observation by fluorescence microscope of cells infected by HIV and stained for immunofluorescence. Human macrophages, immune cells, were extracted from the blood of healthy donors. These were then put into culture and co-infected with HIV and Mycobacterium tuberculosis, the agent responsible for tuberculosis. The infected cells were stained with visible fluorescent antibodies which specifically recognize HIV. These immunofluorescence experiments were designed to monitor the development of the…

Photo
20160102_0031
Cells infected by HIV and stained for immunofluorescence
20160102_0030
Open media modal

Observation by fluorescence microscope of cells infected by HIV and stained for immunofluorescence. Human macrophages, immune cells, were extracted from the blood of healthy donors. These were then put into culture and co-infected with HIV and Mycobacterium tuberculosis, the agent responsible for tuberculosis. The infected cells were stained with visible fluorescent antibodies which specifically recognize HIV. These immunofluorescence experiments were designed to monitor the development of the…

Photo
20160102_0030
Cells infected by HIV and stained for immunofluorescence
20160102_0028
Open media modal

Fixing cells infected by HIV and stained for immunofluorescence on a glass slide. Human macrophages, immune cells, were extracted from the blood of healthy donors. These were then put into culture and co-infected with HIV and Mycobacterium tuberculosis, the agent responsible for tuberculosis. The infected cells were stained with visible fluorescent antibodies which specifically recognize HIV. These immunofluorescence experiments were designed to monitor the development of the HIV infection and…

Photo
20160102_0028
Fixing cells infected by HIV and stained for immunofluorescence on a glass slide
20160102_0027
Open media modal

Fixing cells infected by HIV and stained for immunofluorescence on a glass slide. Human macrophages, immune cells, were extracted from the blood of healthy donors. These were then put into culture and co-infected with HIV and Mycobacterium tuberculosis, the agent responsible for tuberculosis. The infected cells were stained with visible fluorescent antibodies which specifically recognize HIV. These immunofluorescence experiments were designed to monitor the development of the HIV infection and…

Photo
20160102_0027
Fixing cells infected by HIV and stained for immunofluorescence on a glass slide
20160102_0026
Open media modal

Fixing cells infected by HIV and stained for immunofluorescence on a glass slide. Human macrophages, immune cells, were extracted from the blood of healthy donors. These were then put into culture and co-infected with HIV and Mycobacterium tuberculosis, the agent responsible for tuberculosis. The infected cells were stained with visible fluorescent antibodies which specifically recognize HIV. These immunofluorescence experiments were designed to monitor the development of the HIV infection and…

Photo
20160102_0026
Fixing cells infected by HIV and stained for immunofluorescence on a glass slide
20160102_0025
Open media modal

Immunofluorescence staining of cells infected by HIV, previously fixed on a glass slide. Human macrophages, immune cells, were extracted from the blood of healthy donors. These were then put into culture and co-infected with HIV and Mycobacterium tuberculosis, the agent responsible for tuberculosis. The infected cells were stained with visible fluorescent antibodies which specifically recognize HIV. Immunofluorescence is used to track the development of the HIV infection and to understand the…

Photo
20160102_0025
Immunofluorescence staining of cells infected by HIV, previously fixed on a glass slide
20160102_0024
Open media modal

Immunofluorescence staining of cells infected by HIV, previously fixed on a glass slide. Human macrophages, immune cells, were extracted from the blood of healthy donors. These were then put into culture and co-infected with HIV and Mycobacterium tuberculosis, the agent responsible for tuberculosis. The infected cells were stained with visible fluorescent antibodies which specifically recognize HIV. Immunofluorescence is used to track the development of the HIV infection and to understand the…

Photo
20160102_0024
Immunofluorescence staining of cells infected by HIV, previously fixed on a glass slide
20160102_0023
Open media modal

Immunofluorescence staining of cells infected by HIV, previously fixed on a glass slide. Human macrophages, immune cells, were extracted from the blood of healthy donors. These were then put into culture and co-infected with HIV and Mycobacterium tuberculosis, the agent responsible for tuberculosis. The infected cells were stained with visible fluorescent antibodies which specifically recognize HIV. Immunofluorescence is used to track the development of the HIV infection and to understand the…

Photo
20160102_0023
Immunofluorescence staining of cells infected by HIV, previously fixed on a glass slide
20160102_0022
Open media modal

Immunofluorescence staining of cells infected by HIV, previously fixed on a glass slide. Human macrophages, immune cells, were extracted from the blood of healthy donors. These were then put into culture and co-infected with HIV and Mycobacterium tuberculosis, the agent responsible for tuberculosis. The infected cells were stained with visible fluorescent antibodies which specifically recognize HIV. Immunofluorescence is used to track the development of the HIV infection and to understand the…

Photo
20160102_0022
Immunofluorescence staining of cells infected by HIV, previously fixed on a glass slide
20160102_0021
Open media modal

Immunofluorescence staining of cells infected by HIV, previously fixed on a glass slide. Human macrophages, immune cells, were extracted from the blood of healthy donors. These were then put into culture and co-infected with HIV and Mycobacterium tuberculosis, the agent responsible for tuberculosis. The infected cells were stained with visible fluorescent antibodies which specifically recognize HIV. Immunofluorescence is used to track the development of the HIV infection and to understand the…

Photo
20160102_0021
Immunofluorescence staining of cells infected by HIV, previously fixed on a glass slide

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