Sections of murine fibrosarcoma placed on glass slides were circled using an ImmunoMarker
Sections of murine fibrosarcoma induced subcutaneously in mice placed on glass slides were circled using an ImmunoMarker. The fibrosarcoma models spontaneously generated HEV blood vessels (high endothelium veinules) 8 days after induction in the mouse. Researchers were seeking to detect the presence of specific RNA for these blood vessels on the glass slides. They therefore deposited a mixture of antibodies on the sections in order to co-mark the RNA of the vessels. The ImmunoMarker formed a water-repellent barrier around the tumour in order to preserve the antibodies after they have been positioned.