© CNRS Images - 2018

Médaille de l'innovation 2018 : Valérie Castellani

Reference

6570

Duration

00:03:01

Production year

2018

Versions

Original material

HD
16/9
Color
Sound

Director(s)

MIFSUD Nicolas

Résumé

On the occasion of her CNRS innovation medal awarded by the in 2018, Valérie Castellani, a specialist in developmental biology at the NeuroMyoGene Institute, discusses her journey. She conducts fundamental research on the development of the nervous system, with her team.
She works on neuroblastoma, a paediatric cancer of the peripheral nervous system. Her approach was to study this cancer from a developmental biology angle. This has led to the development of a new tumour model, which places human tumour cells in avian embryo tissues, this replicates the evolution of neuroblastoma.
This method enables tumour masses to regenerate in a few days and to obtain metastatic dispersion programmes. An innovation with strong potential that seems to also be applicable to other types of cancer. She co-founded the start-up OncoFactory in 2016 with her colleague Céline Delloye-Bourgeois, with whom she won the Concours Mondial d'Innovation. The start-up aims to use this tumour model in developing predictive biomarkers for personalised medicine and pre-clinical analysis.

Personnalité(s)

CNRS Institute(s)

Regional office(s)

CNRS Images,

Our work is guided by the way scientists question the world around them and we translate their research into images to help people to understand the world better and to awaken their curiosity and wonderment.