Scientific news

In the complexities of the brain

CNRS is organising conferences, workshops and film-discussions about the brain throughout France during the Brain Awareness Week from 11 to 17 March 2024. This is a great opportunity to present you with an overview of research on this intriguing object!

Trajectories of neurotransmitter receptors monitored by single molecule detection on the surface of cultured rat hippocampal neurons.
Trajectoires de récepteurs de neurotransmetteur suivis par détection de molécule unique à la surface de neurones d’hippocampe de rat en culture.

© Benjamin Compans / Daniel Choquet / IINS / CNRS Photothèque

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It is the most complex machine in the world, capable of feats that the most powerful computers are unable to replicate. It is the seat of our personality, our emotions, our ability to appreciate the world around us, the driving force of each of our gestures, in short, the most indispensable organ in the human body. However – and perhaps precisely because it is so complex – the brain is far from having revealed all its secrets. In fact, we will probably never know them all, as if our brain itself were intangible. This is obviously a reason to continue to explore it.

Researchers from very different backgrounds are working tirelessly to crack the mysteries of the human brain one by one, sometimes through the prism of neuroscience, sometimes through that of linguistics, psychology, or social sciences. It raises numerous questions: how do we think? How do we sort (more crucial than ever in the era of increased fake news and attention economics) between “good” and “bad” information? More generally, how do we learn information systems as complex as a language or the common rules of life from an early age? Neurologists and psycholinguists are trying to discover this by conducting series of increasingly more innovative experiments.

Other aspects of the human brain are even more difficult to understand, as they are intangible and unquantifiable… If we were only learning machines, we would be like robots at different stages of development, indistinguishable from each other except for our computing power and the amount of information we have ingested. Yet, we all have distinct personalities, linked in a large part to our creativity and originality. How can we assess them? What are the origins and conditions for their development? This is the subject of fascinating research conducted by scientists.

There is still the question of emotions which are also managed by the brain. How can we measure and understand them? Traumatic events, such as terrorist attacks, are an opportune time to do this, but the barely describable still needs to be able to be translated into analysable data… This is the purpose of the 13-11 research programme, which studies how the memory of the 13 November 2015 attacks is constructed from interviews and notebooks. And trauma means treatment and reconstruction. This is the last major area of research on the human brain: regenerative medicine which aims to help victims of physical or psychological accidents overcome the shock and recover all their capacities. This is an often long and painful road, in which fundamental research is exceedingly useful.

As you will have understood, our brain is an incredibly fascinating area of research, and in this presentation, we invite you to explore its multiple aspects together with the scientists who study it on a daily basis.

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How do babies learn languages? A team of psycholinguists at Babylab is focused on how the structure of sentences is learned, how sounds in language are organised, and the effect on the cognitive development of children based on their social environment. In this film, discover the astonishing experimental protocols used to probe the brains of infants.

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Inside the mind of a baby
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Les sportifs de hauts niveaux ne travaillent pas uniquement leurs muscles, ils entraînent également leurs cerveaux. C'est le cas avec la visualisation mentale. Une équipe de scientifiques du CNRS étudient l'activité cérébrale des athlètes lorsqu'ils s'imaginent réaliser des gestes techniques. Ils ont aussi mis au point un outil à disposition des sportifs pour intégrer l'imagerie motrice dans leur préparation.

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Dans la tête des athlètes
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Nathalie Delprat presents her research on the Augmented Reverie paradigm developed at the Interdisciplinary Laboratory of Digital Sciences (LISN) and more particularly the ELEMENTA project, winner of the CNRS-Image prize 2018. This project concerns the links between virtual materiality, bodily awareness and the imaginary sphere, studied via an immersive and interactive simulation device. The idea is to create virtual representations of the body, which have the physical and dynamic…

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Augmented Reverie
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Dyslexia, autism, rare diseases… What factors are responsible for the neurodevelopmental disorders that affect an increasing number of children? This report features physicians and scientists who study the formation of the brain before birth, using groundbreaking technology: organoids, or miniature simplified replicas of our organs, grown in the laboratory.

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Organoids: laboratory brains for research
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Thanks to the testimonies of 1,000 people, the major research programme "13-November" studies how the memory of the November 2015 attacks is constructed. Information is gathered from emotions, intense memories and nightmares. How can these testimonies be transformed into data that can, then, be analysed by the scientific community?

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From emotion to data
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Emotional or behavioural disorders and irrational fears are the effects of post-traumatic stress disorder that can ruin the lives of victims. A team of neuroscience researchers in Marseille is trying to understand why some patients can recover after a few sessions of EMDR therapy based on eye movement, while others will need several years of treatment.

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Understanding the traumatised brain
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For amputees, controlling a robotic prosthesis is far from a perfect solution. It can take months of training before they can perform basic day-to-day operations. In France, a team of researchers, engineers and medical doctors are developing a more natural method for controlling such a prosthesis using a phenomenon known as phantom limb sensation.

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From Phantom Limb to Bionic Arm
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Can the intonation of somebody's voice tell about their social traits? At IRCAM, researchers conducted experiments to understand how the brain was able to analyse the speech prosody of a speaker, thus demonstrating whether someone is trustworthy or has a domineering attitude towards the person they are talking to. They developed an experimental protocol to understand with which representations in mind one person makes an opinion about the personality of another. Using a phase vocoder, the…

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Greet me and I'll tell you who you are
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Based on research conducted at the Laboratoire d'hydrodynamique (CNRS/Ecole polytechnique), #Sensome has developed ultra-miniaturised sensors that use artificial intelligence to identify the biological nature of tissues in real time. Integrated in the intravascular Clotild™ probe, their technology can, for instance, categorise blood clots in order to help doctors during the treatment of an ischemic stroke.

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Sensome
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La créativité, cette aptitude à proposer idées et concepts originaux et cohérents, est un des grands mystères de notre cerveau, qui passionne psychologues et neuroscientifiques. Différentes expériences sont menées auprès d'adultes et d'enfants pour tenter de comprendre la façon dont le cerveau humain appréhende et surtout génère originalité et nouveauté.

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Demain, tous créatifs ?
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Hundreds of thousands of people in France are affected by a lack of tactile sense. For a long time, this disorder which is difficult to diagnose and assess has hardly been studied. Yet, far from being trivial, hypoesthesia, i.e., a reduction in the sense of touch, can become a real handicap in everyday life. It is common in the elderly and is also associated with many other disorders. This film is a closer look into several multidisciplinary laboratories doing research on understanding the…

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Sense fallen into oblivion (A)
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Fifteen minutes in the strange and fascinating world of our nerve cells. Thanks to time lapse microcinematography, the complex phenomena occuring in the brain are visualized. We can see the birth of nerve cells, we can see them growing, working, dying…. These images brings to the fore two principal actors : the glial cells, building the structure and cleaning the brain, and the neurons, responsible of intercellular communication.

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Neuron time

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