Arbre d’abondance métagénomique d'un microbiome intestinal de souris

Taxonomic tree of dynamic abundance obtained using quantitative metagenomic analysis. This analysis involves identifying associations between a microbiome, different environmental conditions and individuals with particular characteristics (diseases, geographical origin, etc.). Here, research scientists have studied the intestinal microbiome of mice infected with the bacterium Listeria monocytogenes. In this experiment, the abundance of Alloprevotella and Allobaculum bacteria populations is compared to isoleucine S (LLS) gene expression. This image was generated using the SHAMAN (SHiny Application for Metagenomic ANalysis) software package. The recent development of new sequencing technologies means these organisms can be studied at the level of the genome. For Listeria, for example, this allows the identification of new factors contributing to bacterial virulence, notably during the intestinal phase of the infection.