Neurones du cortex sensoriel d’une souris éveillée observés par microscopie de fluorescence

Sensory cortex neurons in an awake mouse viewed using a two-photon excitation fluorescence microscope. The neurons have been transfected with an adeno-associated virus (AAV) used for gene transfer, activating a fluorescent protein sensitive to calcium. The variations in fluorescence over time provide information about the electrical activity of the neurons. The awake mouse undergoes sensory stimulation, potentially learning to respond to it according to a pre-established behavioural protocol. Analysing the activity of neurons helps us understand how the neural network processes sensory information.