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© Frédérique PLAS / CRTI / CNRS Images
Sophie Brouard est lauréate de la médaille de l'Innovation du CNRS 2020
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Sophie Brouard is awarded the CNRS 2020 Innovation Medal. A veterinarian by training, she currently serves as a CNRS research professor at the CRTI (Centre de recherche en transplantation et immunologie – Université de Nantes/Inserm/ITUN/CHU de Nantes). She focuses on alleviating the burden of heavy anti-rejection treatments, which cause numerous side effects. It was originally while looking at the few kidney transplant patients who could forgo treatment that she revealed the B-lymphocyte regulation phenomena and explored the mechanisms through which it occurs, with a view to a possible therapy. Part of her research is also dedicated to identifying biomarkers to evaluate, predict, and diagnose the risk of kidney or lung graft rejection, in an effort to better anticipate and adapt treatments. In partnership with academic colleagues, she has launched two start-ups, TcLand Expression and Effimune, which became OSE Immunotherapeutics, to develop therapeutic tools in various research fields related to cancer and autoimmune diseases