Production year
2012
© Frédéric SAUDOU/SNC/CNRS Images
20120001_0041
The protein huntingtin controls ciliogenesis. When containing the pathogenic polyQ expansion, mutant huntingtin led to abnormally long primary cilia and disorganized cilia layers in mice and humans with Huntingon disease. Longer cilia resulted in alterations of the cerebrospinal fluid flow.
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2012
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