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20170048_0030

© Cyril FRESILLON/CRCA/CNRS Images

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20170048_0030

Une souris explore le bras ouvert d’un labyrinthe en croix

Mouse exploring the open arm of an elevated plus maze. This test can be used to measure anxiety levels in animals. It is based on the natural preference of rodents for closed spaces, which are more reassuring, in comparison to open spaces, which increase anxiety. The less anxious the mouse, the more likely it is to explore the open arms of the maze. By measuring the time spent in the open arms and the closed arms, it is possible to compare the anxiety levels of different mouse lines and evaluate the potential anxiolytic effects of a pharmacological product.

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